Great Dane Puppies for Sale in South Carolina, USA
PuppyFinder.com is your source for finding an ideal Great Dane Puppy for Sale in South Carolina, USA area.
- Great Danes are susceptible to heatstroke due to their size and can overheat quickly in South Carolina's humid summers. Provide plenty of shade, cool water, and limit strenuous outdoor activity during the hottest parts of the day, especially in cities like Columbia which experiences significant heat.
- Regular, low-impact exercise is key. While not high-energy, Danes need walks to maintain their health and prevent obesity. Enjoy leisurely strolls along the coast in Charleston or through greener parks in Greenville, but always be mindful of the heat.
- Their short coat requires minimal grooming, but regular brushing helps reduce shedding. In South Carolina's climate, focus on keeping their living spaces cool and comfortable indoors, as they are prone to seeking air-conditioned havens.
Great Dane puppies are in high demand in South Carolina area. Although there are no direct matches today, please see available puppies below or explore popular Great Dane mixes and other similar dog breeds.
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Great Dane Puppies Available Outside Your Current Filters
AKC Great Dane Litter
$1,000
Litter of 8
Great Dane
Male, 15 Weeks Old
USA WILLIS, TX, USA
Date listed: 08/04/2026
We currently have 4 AKC Great Dane Male Puppies. They will be ready for their forever homes around September 15th. We have harlequins, merles, and a solid black with white...
AKC Black Great Dane Flo
$600
Flo
Great Dane
Female, 14 Weeks Old
USA WILLIS, TX, USA
Date listed: 08/04/2026
Mom - Blue with white markings(140#) Dad - Black with White Markings (170#)
Great Dane litter just in time for holidays
$300
Litter of 2
Great Dane
Female, 7 Weeks Old
USA MAYSVILLE, KY, USA
Date listed: 10/25/2026
Our Millie just has 1 pup left. She is available and will be homed on or after November 4th. Both parents are Great Danes. The mother is 125lbs and the father is a giant 185lbs....
AKC Black Great Dane Maxi
$600
Maxi
Great Dane
Female, 14 Weeks Old
USA WILLIS, TX, USA
Date listed: 08/04/2026
Mom - Blue with white markings(140#) Dad - Black with White Markings (170#)
CKC Great Dane Puppies We are Real People
$800
Litter of 9
Great Dane
Male(s) and Female(s), 16 Weeks Old
USA SPRAGGS, PA, USA
Date listed: 10/05/2026
Our beautiful pups are chock full of personality and eager to give kisses to their new families. 724-435-7912 landline 724-710-5892. text We are an hour below Pittsburgh PA....
Beautiful Great Dane Puppies
$800*
Litter of 12
Great Dane
Male(s) and Female(s), 6 Weeks Old
USA CLANTON, AL, USA
Date listed: 10/20/2026
CKC registered puppies Born on September 19th black, white and gray harlequins with stunning blue eyes 1500, brindle pups, and also mantle pups, black male Pup 800, and blue Merle...
AKC Black Great Dane Pearl
$800
Pearl
Great Dane
Female, 14 Weeks Old
USA WILLIS, TX, USA
Date listed: 08/04/2026
Mom - Blue with white markings(140#) Dad - Black with White Markings (170#)
Fawn Lilac Merle
$3,000
Maple
Great Dane
Female, 7 Weeks Old
USA HALLETTSVILLE, TX, USA
Date listed: 10/11/2026
✨ MEET OUR STUNNING FAWN LILAC MERLE FEMALE! ✨ This girl is the definition of beauty, structure, and personality all wrapped into one incredible Great Dane! ???????? With...
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