Great Dane Puppies for Sale in Missouri, USA

PuppyFinder.com is your source for finding an ideal Great Dane Puppy for Sale in Missouri, USA area.

Considering a majestic Great Dane in Missouri? These gentle giants are increasingly popular among families and individuals seeking a loyal and impressive companion. Their striking appearance, coupled with a famously sweet and patient temperament, makes them a top choice for those looking for a large, yet surprisingly docile, household member. If you're based in Missouri and thinking about adding a Great Dane to your life, understanding their unique needs and how they fit into a family environment is key to a successful adoption. We delve into their suitability for Missouri living, what makes them such a cherished breed, and important considerations before making your purchase.

Great Dane puppies are in high demand in Missouri area. Although there are no direct matches today, please see available puppies below or explore popular Great Dane mixes and other similar dog breeds.

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Beautiful Purebred Great Dane Puppies for sale

$800

Litter of 6

Great Dane

Male(s) and Female(s), 12 Weeks Old

USA DUSHORE, PA, USA

Date listed: 02/24/2026

Tags: Great Dane puppies for sale Pennsylvania dogs Pennsylvania puppy(s) Great Dane Pennsylvania good with kids dog breed low shedding dog breed

5 Beautiful purebred Great Dane (gentle giant) puppies for sale! 3females and 2 males left! They will be ready for their new loving home by April 2026! First shots and checkups...

Beautiful PureBred Great Dane Puppies

$800*

Letter of 10

Great Dane

Male, 7 Weeks Old

USA PITTSBURG, CA, USA

Date listed: 03/16/2026

Tags: California dogs California puppy(s) Great Dane California good with kids dog breed low shedding dog breed

8 boys

Beautiful Great Dane Puppies

$800

Litter of 10

Great Dane

Male(s) and Female(s), 6 Weeks Old

USA CLANTON, AL, USA

Date listed: 03/16/2026

Tags: Alabama dogs Alabama puppy(s) Great Dane Alabama good with kids dog breed low shedding dog breed

CKC registered puppies Born on March 9th 2026 We have beautiful Brindle, Harliquin, Blue and black pups Puppies come with up to date vaccines and Deworming, 2 month Health...

AKC Great Dane Puppy Chariton Iowa

$800

Female 1

Great Dane

Female, 16 Weeks Old

USA RUSSELL, IA, USA

Date listed: 03/24/2026

Tags: Iowa dogs Iowa puppy(s) Great Dane Iowa good with kids dog breed low shedding dog breed

Please feel free to call/text my cell (217)-430-4570 anytime with questions. This litter was born on 12/25/2025 and will be available to go to their new homes in March. They are...

AKC Great Dane Puppy Chariton Iowa

$1,300

Female 3

Great Dane

Female, 16 Weeks Old

USA RUSSELL, IA, USA

Date listed: 03/24/2026

Tags: Iowa dogs Iowa puppy(s) Great Dane Iowa good with kids dog breed low shedding dog breed

Please feel free to call/text my cell (217)-430-4570 anytime with questions. This litter was born on 12/25/2025 and will be available to go to their new homes in March. They are...

Great Dane pups akc all shots rabies tags wormed

$500

Litter of 6

Great Dane

Male(s) and Female(s), 16 Weeks Old

USA ALIQUIPPA, PA, USA

Date listed: 04/17/2026

Tags: Pennsylvania dogs Pennsylvania puppy(s) Great Dane Pennsylvania good with kids dog breed low shedding dog breed

One black and white female, one black and white male, one Harlekin female, one harlequin, male, and one fawn female one fawn male

Chocolate Great Dane

$1,800

Lottie

Great Dane

Female, 5 Months Old

USA HALLETTSVILLE, TX, USA

Date listed: 04/21/2026

Tags: Chocolate Registered Vaccination Texas dogs Texas puppy(s) Great Dane Texas good with kids dog breed low shedding dog breed

AKC Registered Chocolate Great Dane

AKC Great Dane Puppy Chariton Iowa

$1,300

Male 1

Great Dane

Male, 16 Weeks Old

USA RUSSELL, IA, USA

Date listed: 03/24/2026

Tags: Iowa dogs Iowa puppy(s) Great Dane Iowa good with kids dog breed low shedding dog breed

Please feel free to call/text my cell (217)-430-4570 anytime with questions. This litter was born on 12/25/2025 and will be available to go to their new homes in March. They are...

AKC Great Dane Puppy Chariton Iowa

$1,300

Female 4

Great Dane

Female, 16 Weeks Old

USA RUSSELL, IA, USA

Date listed: 03/24/2026

Tags: Iowa dogs Iowa puppy(s) Great Dane Iowa good with kids dog breed low shedding dog breed

Please feel free to call/text my cell (217)-430-4570 anytime with questions. This litter was born on 12/25/2025 and will be available to go to their new homes in March. They are...

AKC Great Dane puppy for sale Wakarusa IN

$1,200

Carol

Great Dane

Female, 5 Months Old

USA WAKARUSA, IN, USA

Date listed: 04/12/2026

Tags: Great Dane Indiana Family Raised Microchipped Puppy AKC European Champion Bloodline Health Guarantee Indiana dogs Indiana puppy(s) Great Dane Indiana good with kids dog breed low shedding dog breed

For more information please call 574-862-2208 anytime Monday - Saturday. AKC Registration, 100% Euro Champion Bloodlines, 2 year health guarantee, microchipped. Crate, leash and...

Great Dane Puppies for Sale in Missouri, USA

Great Dane puppies are in high demand in Missouri area. Although there are no direct matches today, please see available puppies below or explore popular Great Dane mixes and other similar dog breeds.

Great DanePuppies for saleSee all puppies for sale

Breed Mixes of Great Dane

Great Dane Mixed Breed Puppies for Sale

Similar Dog Breeds for Great Dane

Similar Breeds to the Great Dane: Puppies for Sale

Great Dane Puppies Available Outside Your Current Filters

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