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  1. Home
  2. Puppies for Sale
  3. Great Dane
  4. Missouri

Great Dane Puppies for Sale in Missouri, USA

Great Dane

PuppyFinder.com is your source for finding an ideal Great Dane Puppy for Sale in Missouri, USA area.

Finding your gentle giant in the Show-Me State is an exciting journey. Missouri, with its distinct seasons, offers a unique backdrop for raising a majestic Great Dane. Whether you're in the heart of St. Louis, the vibrant streets of Kansas City, or the historic charm of Springfield, a Great Dane can bring a unique presence to your Missouri home.Missouri Great Dane Lifestyle & Care
  • Embrace Missouri's Summers: Great Danes, despite their size, can be sensitive to heat. Ensure your Dane has ample shade and access to cool water, especially during Missouri's humid summer months. Consider indoor play and shaded walks during the hottest parts of the day.
  • Seasonal Coat Care: While Great Danes have short coats, they do shed. Regular brushing helps manage this, particularly as Missouri's seasons change. A good grooming mitt can keep their sleek coats healthy and reduce loose hairs around your home.
  • Socialization in the Midwest: Missouri's friendly spirit mirrors the Great Dane's typically amiable nature. Early and consistent socialization is key, exposing your Dane to various people, environments, and other well-behaved dogs in parks or training classes across the state.
Ready to welcome a loyal companion into your Missouri life? Browse the wonderful Great Dane puppy options available above to find the newest member of your family.

Great Dane puppies are in high demand in Missouri area. Although there are no direct matches today, please see available puppies below or explore popular Great Dane mixes and other similar dog breeds.

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Similar Breeds to the Great Dane: Puppies for Sale

Great Dane Puppies Available Outside Your Current Filters

Fawn Lilac Merle

$3,000
Great Dane Puppy for sale in HALLETTSVILLE, TX, USA Maple

Great Dane

Female, 8 Weeks Old

USA HALLETTSVILLE, TX, USA

Date listed: 10/11/2026

Tags: Great dane Merle Lilac Dane Texas dogs Texas puppy(s) Great Dane Texas good with kids dog breed low shedding dog breed

✨ MEET OUR STUNNING FAWN LILAC MERLE FEMALE! ✨ This girl is the definition of beauty, structure, and personality all wrapped into one incredible Great Dane! ???????? With...

Beautiful Great Dane Puppies

$800*
Great Dane Puppy for sale in CLANTON, AL, USA Litter of 12

Great Dane

Male(s) and Female(s), 7 Weeks Old

USA CLANTON, AL, USA

Date listed: 10/20/2026

Tags: Alabama dogs Alabama puppy(s) Great Dane Alabama good with kids dog breed low shedding dog breed

CKC registered puppies Born on September 19th black, white and gray harlequins with stunning blue eyes 1500, brindle pups, and also mantle pups, black male Pup 800, and blue Merle...

CKC Great Dane Puppies We are Real People

$800
Great Dane Puppy for sale in SPRAGGS, PA, USA Litter of 9

Great Dane

Male(s) and Female(s), 3 Months Old

USA SPRAGGS, PA, USA

Date listed: 11/07/2026

Tags: great dane american great dane Harlequin merle Pennsylvania New York east coast deleware maine Connecticut Rhode Island New Jersey west Virginia Virginia ohio Michigan Missouri North Carolina South Carolina vermont chocolate lilac Chocolate great dane Lilac great dane Chocolate Lilac Pennsylvania dogs Pennsylvania puppy(s) Great Dane Pennsylvania good with kids dog breed low shedding dog breed

Our beautiful pups are chock full of personality and eager to give kisses to their new families. 724-435-7912 landline 724-710-5892. text We are an hour below Pittsburgh PA....

Hope

$500
Great Dane Puppy for sale in SPRAGGS, PA, USA Hope

Great Dane

Female, 4 Years 8 Months Old

USA SPRAGGS, PA, USA

Date listed: 11/07/2026

Tags: Great dane Fawn Female Large breed Pennsylvania dogs Pennsylvania puppy(s) Great Dane Pennsylvania good with kids dog breed low shedding dog breed

Hope is a beautiful spayedCKC registered well trained girl that came back to me due to her owner being sick with cancer. We need to find her a loving home. She is super sweet....
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