Great Dane Puppies for Sale in South Carolina, USA
PuppyFinder.com is your source for finding an ideal Great Dane Puppy for Sale in South Carolina, USA area.
- Great Danes are susceptible to heatstroke due to their size and can overheat quickly in South Carolina's humid summers. Provide plenty of shade, cool water, and limit strenuous outdoor activity during the hottest parts of the day, especially in cities like Columbia which experiences significant heat.
- Regular, low-impact exercise is key. While not high-energy, Danes need walks to maintain their health and prevent obesity. Enjoy leisurely strolls along the coast in Charleston or through greener parks in Greenville, but always be mindful of the heat.
- Their short coat requires minimal grooming, but regular brushing helps reduce shedding. In South Carolina's climate, focus on keeping their living spaces cool and comfortable indoors, as they are prone to seeking air-conditioned havens.
Great Dane puppies are in high demand in South Carolina area. Although there are no direct matches today, please see available puppies below or explore popular Great Dane mixes and other similar dog breeds.
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Breed Mixes of Great Dane
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Similar Breeds to the Great Dane: Puppies for Sale
Great Dane Puppies Available Outside Your Current Filters
Fabulous Great Danes Looking for Furever Family
$2,200
Blue Collar
Great Dane
Male, 6 Weeks Old
USA ALVARADO, TX, USA
Date listed: 07/05/2026
AKC Registration $2,200 (includes deposit) $300 deposit Can pay through Cash App, Zelle, Cash, Cashier's check Zelle: Jamie L. Cox, EECU, (817) 917-7180 Cash App: ...
AKC Great Dane orange collar
$800
Orange
Great Dane
Male, 6 Weeks Old
USA MARSHVILLE, NC, USA
Date listed: 07/12/2026
AKC Great Dane puppy. Will go home with 1st vet exam, 1st vaccines, & deworming already done. You will also receive a Royal Canin puppy pack with food, treats, toys, and...
Great Dane Male
$800
Bluey
Great Dane
Male, 9 Weeks Old
USA GRANBURY, TX, USA
Date listed: 07/08/2026
Great Dane Male Puppy- 8 weeks on July 18th. Mom and Dad on site. In Texas
Great Dane Puppies
$1,500
Litter of 6
Great Dane
Male(s) and Female(s), 10 Weeks Old
USA TEMECULA, CA, USA
Date listed: 07/10/2026
We have 6 Great Danes looking for their forever homes. 3 are boys 3 are girls. Mom is papered, dad is not. Both parents are sweet and loving as most Danes are. Mom is a blue dane...
Fabulous Great Danes Looking for Furever Family
$2,200
Green Collar
Great Dane
Male, 6 Weeks Old
USA ALVARADO, TX, USA
Date listed: 07/05/2026
AKC Registration $2,200 (includes deposit) $300 deposit Can pay through Cash App, Zelle, Cash, Cashier's check Zelle: Jamie L. Cox, EECU, (817) 917-7180 Cash App: ...
Star wars
$700
Litter of 5
Great Dane
Male(s) and Female(s), 11 Weeks Old
USA DANIELSVILLE, GA, USA
Date listed: 06/30/2026
Gorgeous litter of puppies. Affectionate, smart, beautiful coloring. Both parents are registered with CKC. Great around children and all other animals. Will never leave your side....
Light Blue
$1,800
Light blue
Great Dane
Male, 6 Weeks Old
USA MARSHVILLE, NC, USA
Date listed: 07/13/2026
AKC Great Dane puppy BLUE HARLEQUIN Will go home with 1st vet exam, 1st vaccines, & deworming already done. You will also receive a Royal Canin puppy pack with food, treats,...
Fabulous Great Danes Looking for Furever Family
$2,200
Brown Collar
Great Dane
Male, 6 Weeks Old
USA ALVARADO, TX, USA
Date listed: 07/05/2026
AKC Registration $2,200 (includes deposit) $300 deposit Can pay through Cash App, Zelle, Cash, Cashier's check Zelle: Jamie L. Cox, EECU, (817) 917-7180 Cash App: ...
Beautiful Great Dane Puppies
$800*
Litter of 7
Great Dane
Male(s) and Female(s), 7 Weeks Old
USA CLANTON, AL, USA
Date listed: 07/18/2026
CKC registered puppies Born on June 5th black, white and gray female harlequin with stunning blue eyes 1500, black male Pup 800, and blue Merle pups 1300 Puppies come with up to...
ACA Great Dane
$925
Rex
Great Dane
Male, 15 Weeks Old
USA RICHLAND, PA, USA
Date listed: 06/29/2026
This adorable ACA Great Dane puppy is looking for a loving FURever family! Up-to-date with vaccinations, deworming, vet checked and comes with a 1 year genetic health...
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